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Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris

Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ef1e68a632245689a8bf3567ab0778a

Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris

About this item

Full title

Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris

Publisher

London: Taylor & Francis Ltd

Journal title

Emerging microbes & infections, 2024-12, Vol.13 (1), p.2377584

Language

English

Formats

Publication information

Publisher

London: Taylor & Francis Ltd

More information

Scope and Contents

Contents

Introduction: Drug resistance to echinocandins, first-line drugs used to treat Candida auris infection, is rapidly emerging. However, the accumulation of mutations in genes other than FKS1 (before an isolate develops to resistance via FKS1 mutations), remains poorly understood. Methods: Four clinical cases and 29 isolates associated with the increm...

Alternative Titles

Full title

Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9ef1e68a632245689a8bf3567ab0778a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ef1e68a632245689a8bf3567ab0778a

Other Identifiers

ISSN

2222-1751

E-ISSN

2222-1751

DOI

10.1080/22221751.2024.2377584

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