Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components i...
Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimoto’s thyroiditis
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Author / Creator
Zhang, Qian-Yue , Ye, Xiao-Ping , Zhou, Zheng , Zhu, Chen-Fang , Li, Rui , Fang, Ya , Zhang, Rui-Jia , Li, Lu , Liu, Wei , Wang, Zheng , Song, Shi-Yang , Lu, Sang-Yu , Zhao, Shuang-Xia , Lin, Jian-Nan and Song, Huai-Dong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hashimoto’s thyroiditis (HT) is the most common autoimmune disease characterized by lymphocytic infiltration and thyrocyte destruction. Dissection of the interaction between the thyroidal stromal microenvironment and the infiltrating immune cells might lead to a better understanding of HT pathogenesis. Here we show, using single-cell RNA-sequencing...
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Full title
Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimoto’s thyroiditis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9efe0aed643e40f0a6d940fc628988fe
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9efe0aed643e40f0a6d940fc628988fe
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28120-2
