Cystic fibrosis drug ivacaftor stimulates CFTR channels at picomolar concentrations
Cystic fibrosis drug ivacaftor stimulates CFTR channels at picomolar concentrations
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England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The devastating inherited disease cystic fibrosis (CF) is caused by mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) anion channel. The recent approval of the CFTR potentiator drug ivacaftor (Vx-770) for the treatment of CF patients has marked the advent of causative CF therapy. Currently, thousands of patients are being...
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Full title
Cystic fibrosis drug ivacaftor stimulates CFTR channels at picomolar concentrations
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TN_cdi_doaj_primary_oai_doaj_org_article_9f0ba5d4f94c4cbd8af62f68f00391a8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f0ba5d4f94c4cbd8af62f68f00391a8
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.46450
