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Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f12512e066c4896a761008ae6935b13

Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

About this item

Full title

Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-08, Vol.10 (1), p.3495-16, Article 3495

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Immune tolerance to allografts has been pursued for decades as an important goal in transplantation. Administration of apoptotic donor splenocytes effectively induces antigen-specific tolerance to allografts in murine studies. Here we show that two peritransplant infusions of apoptotic donor leukocytes under short-term immunotherapy with antagonist...

Alternative Titles

Full title

Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9f12512e066c4896a761008ae6935b13

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f12512e066c4896a761008ae6935b13

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-11338-y

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