Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes
Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes
About this item
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Author / Creator
Singh, Amar , Ramachandran, Sabarinathan , Graham, Melanie L. , Daneshmandi, Saeed , Heller, David , Suarez-Pinzon, Wilma Lucia , Balamurugan, Appakalai N. , Ansite, Jeffrey D. , Wilhelm, Joshua J. , Yang, Amy , Zhang, Ying , Palani, Nagendra P. , Abrahante, Juan E. , Burlak, Christopher , Miller, Stephen D. , Luo, Xunrong and Hering, Bernhard J.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Immune tolerance to allografts has been pursued for decades as an important goal in transplantation. Administration of apoptotic donor splenocytes effectively induces antigen-specific tolerance to allografts in murine studies. Here we show that two peritransplant infusions of apoptotic donor leukocytes under short-term immunotherapy with antagonist...
Alternative Titles
Full title
Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes
Authors, Artists and Contributors
Author / Creator
Ramachandran, Sabarinathan
Graham, Melanie L.
Daneshmandi, Saeed
Heller, David
Suarez-Pinzon, Wilma Lucia
Balamurugan, Appakalai N.
Ansite, Jeffrey D.
Wilhelm, Joshua J.
Yang, Amy
Zhang, Ying
Palani, Nagendra P.
Abrahante, Juan E.
Burlak, Christopher
Miller, Stephen D.
Luo, Xunrong
Hering, Bernhard J.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9f12512e066c4896a761008ae6935b13
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f12512e066c4896a761008ae6935b13
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11338-y