Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related m...
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life
About this item
Full title
Author / Creator
Hata, Masayuki , Hata, Maki , Andriessen, Elisabeth Mma , Juneau, Rachel , Pilon, Frédérique , Crespo-Garcia, Sergio , Diaz-Marin, Roberto , Guber, Vera , Binet, Francois , Fournier, Frédérik , Buscarlet, Manuel , Grou, Caroline , Calderon, Virginie , Heckel, Emilie , Melichar, Heather J , Joyal, Jean-Sebastien , Wilson, Ariel M and Sapieha, Przemyslaw
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Pathological neovascularization in age-related macular degeneration (nvAMD) drives the principal cause of blindness in the elderly. While there is a robust genetic association between genes of innate immunity and AMD, genome-to-phenome relationships are low, suggesting a critical contribution of environmental triggers of disease. Possible insight c...
Alternative Titles
Full title
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life
Authors, Artists and Contributors
Author / Creator
Hata, Maki
Andriessen, Elisabeth Mma
Juneau, Rachel
Pilon, Frédérique
Crespo-Garcia, Sergio
Diaz-Marin, Roberto
Guber, Vera
Binet, Francois
Fournier, Frédérik
Buscarlet, Manuel
Grou, Caroline
Calderon, Virginie
Heckel, Emilie
Melichar, Heather J
Joyal, Jean-Sebastien
Wilson, Ariel M
Sapieha, Przemyslaw
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9f2a87e18ff945d5802827bcdccf47e0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f2a87e18ff945d5802827bcdccf47e0
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI159757
