Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic...
Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Directed evolution has long been a key strategy to generate enzymes with desired properties like high selectivity, but experimental barriers and analytical costs of screening enormous mutant libraries have limited such efforts. Here, we describe an ultrahigh-throughput dual-channel microfluidic droplet screening system that can be used to screen up...
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Efficient molecular evolution to generate enantioselective enzymes using a dual-channel microfluidic droplet screening platform
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TN_cdi_doaj_primary_oai_doaj_org_article_9f4f01f54d654f369fd23c54de3aefef
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f4f01f54d654f369fd23c54de3aefef
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03492-6
