Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Anal...
Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells
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Author / Creator
Sun, Xiao , Lu, Zhanying , Liang, Zhenzhen , Deng, Bowen , Zhu, Yuping , Shi, Jing and Lu, Xiaoling
Publisher
Basel: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Basel: MDPI AG
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Scope and Contents
Contents
The present study is to explore the anticancer effect of loonamycin (LM) in vitro and in vivo, and investigate the underlying mechanism with combined multi-omics. LM exhibited anticancer activity in human triple negative breast cancer cells by promoting cell apoptosis. LM administration inhibited the growth of MDA-MB-468 tumors in a murine xenograf...
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Full title
Transcriptomics and Proteomics Characterizing the Anticancer Mechanisms of Natural Rebeccamycin Analog Loonamycin in Breast Cancer Cells
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9f63f173fc2142d999e950b10c18db42
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9f63f173fc2142d999e950b10c18db42
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27206958
