miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration i...
miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects
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Author / Creator
Yang, Chi , Liu, Xiaohan , Zhao, Kai , Zhu, Youming , Hu, Bin , Zhou, Yong , Wang, Mohan , Wu, Yiqun , Zhang, Chengfei , Xu, Jianguang , Ning, Yujie and Zou, Duohong
Publisher
England: BioMed Central
Journal title
Language
English
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Publisher
England: BioMed Central
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Contents
Functional reconstruction of maxillofacial bone defects is a considerable clinical challenge. Many studies have emphasized the osteogenic and angiopoietic abilities of stem cells for tissue regeneration. We previously showed that microRNA-21 (miRNA-21) can promote angiogenesis in human umbilical cord blood-derived mesenchymal stem cells (UCBMSCs)....
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Full title
miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9fb949688acd406596b214bb76077090
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9fb949688acd406596b214bb76077090
Other Identifiers
ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-019-1168-2
