Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters
Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters
About this item
Full title
Author / Creator
Ihle, Michaela A. , Heydt, Carina , Schultheis, Anne Maria , Stöhr, Robert , Haller, Florian , Herold, Sylvia , Aust, Daniela , Dietmaier, Wolfgang , Evert, Matthias , Eszlinger, Markus , Haak, Anja , Laßmann, Silke , Vorholt, Daniela , Breitenbücher, Frank , Werner, Martin , Streubel, Anna , Mairinger, Thomas , Grassow-Narlik, Maja and Merkelbach-Bruse, Sabine
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Insertion mutations in exon 20 of the epidermal growth factor receptor gene (
EGFR
exon20ins) are rare, heterogeneous alterations observed in non-small cell lung cancer (NSCLC). With a few exceptions, they are associated with primary resistance to established EGFR tyrosine kinase inhibitors (TKIs). As patients carrying
EGFR
exon20ins ma...
Alternative Titles
Full title
Multinational proficiency tests for EGFR exon 20 insertions reveal that the assay design matters
Authors, Artists and Contributors
Author / Creator
Heydt, Carina
Schultheis, Anne Maria
Stöhr, Robert
Haller, Florian
Herold, Sylvia
Aust, Daniela
Dietmaier, Wolfgang
Evert, Matthias
Eszlinger, Markus
Haak, Anja
Laßmann, Silke
Vorholt, Daniela
Breitenbücher, Frank
Werner, Martin
Streubel, Anna
Mairinger, Thomas
Grassow-Narlik, Maja
Merkelbach-Bruse, Sabine
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9fbf9687d08840bb993f42908b606080
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9fbf9687d08840bb993f42908b606080
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-63821-2
