Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells
Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Glioblastoma (GBM) is an incurable form of primary astrocytic brain tumor driven by glioma stem cell (GSC) compartment closely associated with the vascular niche. GSC phenotypes are heterogeneous and range from proneural to mesenchymal-like, the latter characterised by greater invasiveness. Here we document the secretory (angiocrine) role of endoth...
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Angiocrine extracellular vesicles impose mesenchymal reprogramming upon proneural glioma stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_9fc37250e87a4721843dcf75d51a9476
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9fc37250e87a4721843dcf75d51a9476
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33235-7
