ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidne...
ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Decreased ATP Binding Cassette Transporter A1 (ABCA1) expression and caspase-4-mediated noncanonical inflammasome contribution have been described in podocytes in diabetic kidney disease (DKD). To investigate a link between these pathways, we evaluated pyroptosis-related mediators in human podocytes with stable knockdown of ABCA1 (siABCA1) and foun...
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ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease
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TN_cdi_doaj_primary_oai_doaj_org_article_9ff64306c5904d43921755a62b6da09d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ff64306c5904d43921755a62b6da09d
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-35499-5
