Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and eff...
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Hematopoietic stem cell transplantation (HSCT) is a curative therapy for blood and immune diseases with potential for many settings beyond current standard-of-care. Broad HSCT application is currently precluded largely due to morbidity and mortality associated with genotoxic irradiation or chemotherapy conditioning. Here we show that a single dose...
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Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
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TN_cdi_doaj_primary_oai_doaj_org_article_9ffac621975f4bccb6eaeafd10b5ba55
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ffac621975f4bccb6eaeafd10b5ba55
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-08201-x
