FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in sing...
FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in single-cell RNA-sequencing datasets
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Publisher
London: BioMed Central
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Language
English
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London: BioMed Central
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Contents
Cell type-specific differential gene expression analyses based on single-cell transcriptome datasets are sensitive to the presence of cell-free mRNA in the droplets containing single cells. This so-called ambient RNA contamination may differ between samples obtained from patients and healthy controls. Current ambient RNA correction methods were not...
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Full title
FastCAR: fast correction for ambient RNA to facilitate differential gene expression analysis in single-cell RNA-sequencing datasets
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TN_cdi_doaj_primary_oai_doaj_org_article_a0130c8b773f4ba59f2841d6236751c7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0130c8b773f4ba59f2841d6236751c7
Other Identifiers
ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/s12864-023-09822-3
