Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation...
Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage
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Author / Creator
Carotenuto, Pietro , Amato, Francesco , Lampis, Andrea , Rae, Colin , Hedayat, Somaieh , Previdi, Maria C. , Zito, Domenico , Raj, Maya , Guzzardo, Vincenza , Sclafani, Francesco , Lanese, Andrea , Parisi, Claudia , Vicentini, Caterina , Said-Huntingford, Ian , Hahne, Jens C. , Hallsworth, Albert , Kirkin, Vladimir , Young, Kate , Begum, Ruwaida , Wotherspoon, Andrew , Kouvelakis, Kyriakos , Azevedo, Sergio Xavier , Michalarea, Vasiliki , Upstill-Goddard, Rosie , Rao, Sheela , Watkins, David , Starling, Naureen , Sadanandam, Anguraj , Chang, David K. , Biankin, Andrew V. , Jamieson, Nigel B. , Scarpa, Aldo , Cunningham, David , Chau, Ian , Workman, Paul , Fassan, Matteo , Valeri, Nicola and Braconi, Chiara
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
FOLFIRINOX, a combination of chemotherapy drugs (Fluorouracil, Oxaliplatin, Irinotecan -FOI), provides the best clinical benefit in pancreatic ductal adenocarcinoma (PDAC) patients. In this study we explore the role of miRNAs (MIR) as modulators of chemosensitivity to identify potential biomarkers of response. We find that 41 and 84 microRNA inhibi...
Alternative Titles
Full title
Modulation of pancreatic cancer cell sensitivity to FOLFIRINOX through microRNA-mediated regulation of DNA damage
Authors, Artists and Contributors
Author / Creator
Amato, Francesco
Lampis, Andrea
Rae, Colin
Hedayat, Somaieh
Previdi, Maria C.
Zito, Domenico
Raj, Maya
Guzzardo, Vincenza
Sclafani, Francesco
Lanese, Andrea
Parisi, Claudia
Vicentini, Caterina
Said-Huntingford, Ian
Hahne, Jens C.
Hallsworth, Albert
Kirkin, Vladimir
Young, Kate
Begum, Ruwaida
Wotherspoon, Andrew
Kouvelakis, Kyriakos
Azevedo, Sergio Xavier
Michalarea, Vasiliki
Upstill-Goddard, Rosie
Rao, Sheela
Watkins, David
Starling, Naureen
Sadanandam, Anguraj
Chang, David K.
Biankin, Andrew V.
Jamieson, Nigel B.
Scarpa, Aldo
Cunningham, David
Chau, Ian
Workman, Paul
Fassan, Matteo
Valeri, Nicola
Braconi, Chiara
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a029501cd4ea4989bf6d137ae286835e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a029501cd4ea4989bf6d137ae286835e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27099-6
