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Human B cell lineages associated with germinal centers following influenza vaccination are measurabl...

Human B cell lineages associated with germinal centers following influenza vaccination are measurabl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a02d4d2d2cdd46088337aeb5a30242a5

Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving

About this item

Full title

Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2021-11, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

The poor efficacy of seasonal influenza virus vaccines is often attributed to pre-existing immunity interfering with the persistence and maturation of vaccine-induced B cell responses. We previously showed that a subset of vaccine-induced B cell lineages are recruited into germinal centers (GCs) following vaccination, suggesting that affinity matur...

Alternative Titles

Full title

Human B cell lineages associated with germinal centers following influenza vaccination are measurably evolving

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a02d4d2d2cdd46088337aeb5a30242a5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a02d4d2d2cdd46088337aeb5a30242a5

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.70873

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