Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic mark...
Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation
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Author / Creator
Korshunov, Andrey , Okonechnikov, Konstantin , Schmitt-Hoffner, Felix , Ryzhova, Marina , Sahm, Felix , Stichel, Damian , Schrimpf, Daniel , Reuss, David E , Sievers, Philipp , Suwala, Abigail Kora , Kumirova, Ella , Zheludkova, Olga , Golanov, Andrey , Jones, David T W , Pfister, Stefan M , Kool, Marcel and von Deimling, Andreas
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly malignant neoplasms posing diagnostic challenge due to a lack of defining molecular markers. CNS neuroblastoma with forkhead box R2 (FOXR2) activation (CNS_NBL) emerged as a distinct pediatric brain tumor entity from a pool previously diagnosed as primitive neuroe...
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Full title
Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation
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TN_cdi_doaj_primary_oai_doaj_org_article_a03757785fc54aa38022bafffc802d35
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a03757785fc54aa38022bafffc802d35
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01118-5
