Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediat...
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
About this item
Full title
Author / Creator
Gonzalez-Meljem, Jose Mario , Haston, Scott , Carreno, Gabriela , Apps, John R. , Pozzi, Sara , Stache, Christina , Kaushal, Grace , Virasami, Alex , Panousopoulos, Leonidas , Mousavy-Gharavy, Seyedeh Neda , Guerrero, Ana , Rashid, Mamunur , Jani, Nital , Goding, Colin R. , Jacques, Thomas S. , Adams, David J. , Gil, Jesus , Andoniadou, Cynthia L. and Martinez-Barbera, Juan Pedro
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Senescent cells may promote tumour progression through the activation of a senescence-associated secretory phenotype (SASP), whether these cells are capable of initiating tumourigenesis in vivo is not known. Expression of oncogenic β-catenin in Sox2+ young adult pituitary stem cells leads to formation of clusters of stem cells and induction of tumo...
Alternative Titles
Full title
Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma
Authors, Artists and Contributors
Author / Creator
Haston, Scott
Carreno, Gabriela
Apps, John R.
Pozzi, Sara
Stache, Christina
Kaushal, Grace
Virasami, Alex
Panousopoulos, Leonidas
Mousavy-Gharavy, Seyedeh Neda
Guerrero, Ana
Rashid, Mamunur
Jani, Nital
Goding, Colin R.
Jacques, Thomas S.
Adams, David J.
Gil, Jesus
Andoniadou, Cynthia L.
Martinez-Barbera, Juan Pedro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a0474958863a4634a3e1c6faf8951dc5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0474958863a4634a3e1c6faf8951dc5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01992-5
