Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain
Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Viral protein 35 (VP35) of Ebola virus (EBOV) is a multifunctional protein that mainly acts as a viral polymerase cofactor and an interferon antagonist. VP35 interacts with the viral nucleoprotein (NP) and double-stranded RNA for viral RNA transcription/replication and inhibition of type I interferon (IFN) production, respectively. The C-terminal p...
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Full title
Functional Importance of Hydrophobic Patches on the Ebola Virus VP35 IFN-Inhibitory Domain
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TN_cdi_doaj_primary_oai_doaj_org_article_a0527a5bb6704eb7a1e2b8a7c96745d7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0527a5bb6704eb7a1e2b8a7c96745d7
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ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v13112316
