Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Pla...
Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Plasticity
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Cairo, Egypt: Hindawi Publishing Corporation
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Language
English
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Contents
Alzheimer's disease (AD) is a neurodegenerative disease, one of whose major pathological hallmarks is the accumulation of amyloid plaques comprised of aggregated β-amyloid (Aβ) peptides. It is now recognized that soluble Aβ oligomers may lead to synaptic dysfunctions early in AD pathology preceding plaque deposition. Aβ is produced by a sequential...
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Full title
Consequences of Inhibiting Amyloid Precursor Protein Processing Enzymes on Synaptic Function and Plasticity
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TN_cdi_doaj_primary_oai_doaj_org_article_a055dac9f90648fe90bdaa913f17da81
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a055dac9f90648fe90bdaa913f17da81
Other Identifiers
ISSN
2090-5904
E-ISSN
1687-5443
DOI
10.1155/2012/272374
