Exosomal lncRNA UCA1 modulates cervical cancer stem cell self-renewal and differentiation through mi...
Exosomal lncRNA UCA1 modulates cervical cancer stem cell self-renewal and differentiation through microRNA-122-5p/SOX2 axis
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Author / Creator
Gao, Zhihui , Wang, Qianqing , Ji, Mei , Guo, Xiangcui , Li, Li and Su, Xiaoke
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Background There is growing evidence discussing the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). We performed this study to explore the impact of exosomal lncRNA urothelial cancer-associated 1 (UCA1) in CC stem cells by sponging microRNA-122-5p (miR-122-5p) and regulating SOX2 expression. Methods CC stem cells (CD133.sup.+CaSki)...
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Full title
Exosomal lncRNA UCA1 modulates cervical cancer stem cell self-renewal and differentiation through microRNA-122-5p/SOX2 axis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a063c325f4b2446b950407f64d3a5a44
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a063c325f4b2446b950407f64d3a5a44
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-021-02872-9
