Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitiv...
Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Despite an early response to platinum-based chemotherapy in advanced stage high-grade serous ovarian cancer (HGSOC), the majority of patients will relapse with drug-resistant disease. Aberrant epigenetic alterations like DNA methylation are common in HGSOC. Differences in DNA methylation are associated with chemoresponse in these patients. The obje...
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Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_a06eb7d5a96d40b0ba2f31f1bb438006
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a06eb7d5a96d40b0ba2f31f1bb438006
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ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/s12916-017-0870-0
