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Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0985c5563bd43b498daec3196d6c305

Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

About this item

Full title

Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-01, Vol.11 (1), p.370-370, Article 370

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The human Mre11/Rad50 complex is one of the key factors in genome maintenance pathways. Previous nanoscale imaging by atomic force microscopy (AFM) showed that the ring-like structure of the human Mre11/Rad50 complex transiently opens at the zinc hook of Rad50. However, imaging of the human Mre11/Rad50 complex by high-speed AFM shows that the Rad50...

Alternative Titles

Full title

Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a0985c5563bd43b498daec3196d6c305

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0985c5563bd43b498daec3196d6c305

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-14025-0

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