APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder
APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder
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Switzerland: Frontiers Media S.A
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English
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Switzerland: Frontiers Media S.A
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Metabolites of the Amyloid-β precursor protein (APP) proteolysis may underlie brain overgrowth in Autism Spectrum Disorder (ASD). We have found elevated APP metabolites (total APP, secreted (s) APPα, and α-secretase adamalysins in the plasma and brain tissue of children with ASD). In this review, we highlight several lines of evidence supporting AP...
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APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder
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TN_cdi_doaj_primary_oai_doaj_org_article_a0cf2b1c003f46d5abdd97b2a6f33831
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0cf2b1c003f46d5abdd97b2a6f33831
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2023.1201744
