Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increase...
Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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X-linked lymphoproliferative disease (XLP) is either caused by loss of the SLAM-associated protein (SAP; XLP-1) or the X-linked inhibitor of apoptosis (XIAP; XLP-2). In both instances, infection with the oncogenic human Epstein Barr virus (EBV) leads to pathology, but EBV-associated lymphomas only emerge in XLP-1 patients. Therefore, we investigate...
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Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1
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TN_cdi_doaj_primary_oai_doaj_org_article_a0e5da340b41418f9bd4969add63331b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0e5da340b41418f9bd4969add63331b
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-05337-z
