Synthesis, Biological Evaluation, and Structure-Activity Relationships of 4-Aminopiperidines as Nove...
Synthesis, Biological Evaluation, and Structure-Activity Relationships of 4-Aminopiperidines as Novel Antifungal Agents Targeting Ergosterol Biosynthesis
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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The aliphatic heterocycles piperidine and morpholine are core structures of well-known antifungals such as fenpropidin and fenpropimorph, commonly used as agrofungicides, and the related morpholine amorolfine is approved for the treatment of dermal mycoses in humans. Inspired by these lead structures, we describe here the synthesis and biological e...
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Synthesis, Biological Evaluation, and Structure-Activity Relationships of 4-Aminopiperidines as Novel Antifungal Agents Targeting Ergosterol Biosynthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_a0f65cc090474ba8b727559d6d19935f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0f65cc090474ba8b727559d6d19935f
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26237208
