Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis
Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis
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Author / Creator
Yuan, Yanmei , Xu, Junting , Jiang, Quanxin , Yang, Chuanxin , Wang, Ning , Liu, Xiaolong , Piao, Hai-long , Lu, Sijia , Zhang, Xianjing , Han, Liu , Liu, Zhiyan , Cai, Jiabin , Liu, Fang , Chen, Suzhen and Liu, Junli
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Targeting ferroptosis has been identified as a promising approach for the development of cancer therapies. Monounsaturated fatty acid (MUFA) is a type of lipid that plays a crucial role in inhibiting ferroptosis. Ficolin 3 (FCN3) is a component of the complement system, serving as a recognition molecule against pathogens in the lectin pathway. Rece...
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Full title
Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_a0fde06c913349df8656e2b1aeadc564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0fde06c913349df8656e2b1aeadc564
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-024-03047-2
