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C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps

C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a119f5892a0d43a4859a59ccd6f0ea4d

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has potent proinflammatory actions and plays immunopathological roles in inflammatory diseases, we investiga...

Alternative Titles

Full title

C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a119f5892a0d43a4859a59ccd6f0ea4d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a119f5892a0d43a4859a59ccd6f0ea4d

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI163105

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