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Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a11caf6fe99a446c89f73b3b14c0a54b

Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

About this item

Full title

Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

Publisher

Germany: BioMed Central Ltd

Journal title

Clinical epigenetics, 2025-02, Vol.17 (1), p.21-15

Language

English

Formats

Publication information

Publisher

Germany: BioMed Central Ltd

More information

Scope and Contents

Contents

Maternal hormonal status can have long-term effects on offspring metabolic health and is likely regulated via epigenetic mechanisms. We elucidated the effects of maternal thyroid hormones on the epigenetic regulation of leptin (Lep) transcription in adipose tissue (AT) and subsequently investigated the role of DNA methylation at a Lep upstream enha...

Alternative Titles

Full title

Sex-specific role of epigenetic modification of a leptin upstream enhancer in adipose tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a11caf6fe99a446c89f73b3b14c0a54b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a11caf6fe99a446c89f73b3b14c0a54b

Other Identifiers

ISSN

1868-7075,1868-7083

E-ISSN

1868-7083

DOI

10.1186/s13148-025-01830-2

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