Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem c...
Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells
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Full title
Author / Creator
Cencioni, Chiara , Spallotta, Francesco , Savoia, Matteo , Kuenne, Carsten , Guenther, Stefan , Re, Agnese , Wingert, Susanne , Rehage, Maike , Sürün, Duran , Siragusa, Mauro , Smith, Jacob G. , Schnütgen, Frank , von Melchner, Harald , Rieger, Michael A. , Martelli, Fabio , Riccio, Antonella , Fleming, Ingrid , Braun, Thomas , Zeiher, Andreas M. , Farsetti, Antonella and Gaetano, Carlo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Nitric oxide (NO) synthesis is a late event during differentiation of mouse embryonic stem cells (mESC) and occurs after release from serum and leukemia inhibitory factor (LIF). Here we show that after release from pluripotency, a subpopulation of mESC, kept in the naive state by 2i/LIF, expresses endothelial nitric oxide synthase (eNOS) and endoge...
Alternative Titles
Full title
Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells
Authors, Artists and Contributors
Author / Creator
Spallotta, Francesco
Savoia, Matteo
Kuenne, Carsten
Guenther, Stefan
Re, Agnese
Wingert, Susanne
Rehage, Maike
Sürün, Duran
Siragusa, Mauro
Smith, Jacob G.
Schnütgen, Frank
von Melchner, Harald
Rieger, Michael A.
Martelli, Fabio
Riccio, Antonella
Fleming, Ingrid
Braun, Thomas
Zeiher, Andreas M.
Farsetti, Antonella
Gaetano, Carlo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a14bcea599a241e4b7bb31b5f8b2ac2b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a14bcea599a241e4b7bb31b5f8b2ac2b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03668-0