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Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Vi...

Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Vi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a155677129a94404a6fc5cb1c5e4033b

Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Virus Infected Patients in a Portuguese Cohort

About this item

Full title

Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Virus Infected Patients in a Portuguese Cohort

Publisher

Switzerland: MDPI AG

Journal title

Viruses, 2018-04, Vol.10 (5), p.223

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

This study is focused on the prevalent NS5 coding region resistance-associated substitutions (RASs) in DAA-naive genotype (GT)1 HCV-infected patients and their potential impact on success rates. Plasma RNA from 81 GT1 HCV-infected patients was extracted prior to an in-house nested RT-PCR of the NS5 coding region, which is followed by Sanger populat...

Alternative Titles

Full title

Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Virus Infected Patients in a Portuguese Cohort

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a155677129a94404a6fc5cb1c5e4033b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a155677129a94404a6fc5cb1c5e4033b

Other Identifiers

ISSN

1999-4915

E-ISSN

1999-4915

DOI

10.3390/v10050223

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