PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273
PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273
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Publisher
Switzerland: MDPI
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Language
English
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Publisher
Switzerland: MDPI
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Contents
Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipose tissue biology. In obesity, phosphorylation of PPARγ at Ser273 (pSer273) by cyclin-dependent kinase 5 (CDK5)/extracellular signal-regulated kinase (ERK) orchestrates diabetic gene reprogramming via dysregulation of specific gene expression. Although many recent st...
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Full title
PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273
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TN_cdi_doaj_primary_oai_doaj_org_article_a198bc4de1234390b827a6c4f2a6e969
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a198bc4de1234390b827a6c4f2a6e969
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9020343
