Growth factors and mechano-regulated reciprocal crosstalk with extracellular matrix tune the keratoc...
Growth factors and mechano-regulated reciprocal crosstalk with extracellular matrix tune the keratocyte–fibroblast/myofibroblast transition
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Improper healing of the cornea after injury, infections or surgery can lead to corneal scar formation, which is associated with the transition of resident corneal keratocytes into activated fibroblasts and myofibroblasts (K–F/M). Myofibroblasts can create an extracellular matrix (ECM) niche in which fibrosis is promoted and perpetuated, resulting i...
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Growth factors and mechano-regulated reciprocal crosstalk with extracellular matrix tune the keratocyte–fibroblast/myofibroblast transition
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TN_cdi_doaj_primary_oai_doaj_org_article_a1b25b4b9d89461fa0f03d5897312cc3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a1b25b4b9d89461fa0f03d5897312cc3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-37776-9