Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently...
Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Evidence exists that chronic antidepressant therapy enhances CREB levels and activity. Nevertheless, the data are not conclusive, as previous analysis of transgenic mouse models has suggested that CREB inactivation in fact contributes to antidepressant-like behavior. The aim of this study was to evaluate the role of CREB in this context by exploiti...
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Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test
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TN_cdi_doaj_primary_oai_doaj_org_article_a1b7e3eb2dd2473daa4f073cdd043deb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a1b7e3eb2dd2473daa4f073cdd043deb
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-14069-6
