Small nucleoli are a cellular hallmark of longevity
Small nucleoli are a cellular hallmark of longevity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Animal lifespan is regulated by conserved metabolic signalling pathways and specific transcription factors, but whether these pathways affect common downstream mechanisms remains largely elusive. Here we show that NCL-1/TRIM2/Brat tumour suppressor extends lifespan and limits nucleolar size in the major
C. elegans
longevity pathways, as part...
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Full title
Small nucleoli are a cellular hallmark of longevity
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TN_cdi_doaj_primary_oai_doaj_org_article_a1c21506b6f54e62bbf007f51e842a46
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a1c21506b6f54e62bbf007f51e842a46
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms16083
