Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and...
Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies
About this item
Full title
Author / Creator
Publisher
England: Taylor & Francis
Journal title
Language
English
Formats
Publication information
Publisher
England: Taylor & Francis
Subjects
More information
Scope and Contents
Contents
Topoisomerase II (TOP-2) is a promising molecular target for cancer therapy. Numerous antibiotics could interact with biologically relevant macromolecules and provoke antitumor potential. Herein, molecular docking studies were used to investigate the binding interactions of 138 antibiotics against the human topoisomerase II-DNA complex. Followed by...
Alternative Titles
Full title
Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a1c855bf5ade4c9380cb028408c47807
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a1c855bf5ade4c9380cb028408c47807
Other Identifiers
ISSN
1475-6366
E-ISSN
1475-6374
DOI
10.1080/14756366.2023.2171029
