Early commitment and robust differentiation in colonic crypts
Early commitment and robust differentiation in colonic crypts
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Tissue stem cells produce a constant flux of differentiated cells with distinct proportions. Here, we show that stem cells in colonic crypts differentiate early to form precisely 1:3 ratio of secretory to absorptive cells. This precision is surprising, as there are only eight stem cells making irreversible fate decisions, and so large stochastic ef...
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Full title
Early commitment and robust differentiation in colonic crypts
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TN_cdi_doaj_primary_oai_doaj_org_article_a1f0791550cc4955a50f9c9ebe2c5e5f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a1f0791550cc4955a50f9c9ebe2c5e5f
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.15252/msb.20167283
