Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes
Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Hsp70 participates in a broad spectrum of protein folding processes extending from nascent chain folding to protein disaggregation. This versatility in function is achieved through a diverse family of J-protein cochaperones that select substrates for Hsp70. Substrate selection is further tuned by transient complexation between different classes of...
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Full title
Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes
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TN_cdi_doaj_primary_oai_doaj_org_article_a20258da37e549069a38cb1d780a7bdf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a20258da37e549069a38cb1d780a7bdf
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.24560
