Neuroprotective effect of Dl-3-n-butylphthalide against ischemia–reperfusion injury is mediated by f...
Neuroprotective effect of Dl-3-n-butylphthalide against ischemia–reperfusion injury is mediated by ferroptosis regulation via the SLC7A11/GSH/GPX4 pathway and the attenuation of blood–brain barrier disruption
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Author / Creator
Xu, Shuangli , Li, Xuewei , Li, Yutian , Li, Xiangling , Lv, E. , Zhang, Xiaojun , Shi, Youkui and Wang, Yanqiang
Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Stroke is one of the most severe diseases worldwide, resulting in physical and mental problems. Dl-3-n-butylphthalide, a compound derived from celery seed, has been approved for treating ischemic stroke in China. No study has evaluated how Dl-3-n-butylphthalide affects the ferroptosis SLC7A11/GSH/GPX4 signal pathway and blood-brain barrier (BBB) PD...
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Full title
Neuroprotective effect of Dl-3-n-butylphthalide against ischemia–reperfusion injury is mediated by ferroptosis regulation via the SLC7A11/GSH/GPX4 pathway and the attenuation of blood–brain barrier disruption
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TN_cdi_doaj_primary_oai_doaj_org_article_a20cb4119d2348ae8c81ccce64b29eba
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a20cb4119d2348ae8c81ccce64b29eba
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2023.1028178