An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydo...
An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Silencing of exogenous DNA can make transgene expression very inefficient. Genetic screens in the model alga
Chlamydomonas
have demonstrated that transgene silencing can be overcome by mutations in unknown gene(s), thus producing algal strains that stably express foreign genes to high levels. Here, we show that the silencing mechanism specifi...
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Full title
An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas
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TN_cdi_doaj_primary_oai_doaj_org_article_a20d8d3521784cf38c6e1a4183cbef92
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a20d8d3521784cf38c6e1a4183cbef92
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19983-4
