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Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma...

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a26f90bf8cc0433899cc58d86f6073bb

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

About this item

Full title

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

Publisher

United States: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2021-02, Vol.15 (2), p.e0009132-e0009132

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In
Trypanosoma brucei
, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete enzymes, five of which possess putative peroxisome targeting sequences. Published experi...

Alternative Titles

Full title

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a26f90bf8cc0433899cc58d86f6073bb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a26f90bf8cc0433899cc58d86f6073bb

Other Identifiers

ISSN

1935-2735,1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0009132

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