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Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduc...

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a278319ae4704e5a8526dd27afba4ede

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

About this item

Full title

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

Publisher

England: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2010-11, Vol.5 (1), p.45-45, Article 45

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

It has traditionally been thought that the pathological accumulation of tau in Alzheimer's disease and other tauopathies facilitates neurodegeneration, which in turn leads to cognitive impairment. However, recent evidence suggests that tau tangles are not the entity responsible for memory loss, rather it is an intermediate tau species that disrupts...

Alternative Titles

Full title

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a278319ae4704e5a8526dd27afba4ede

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a278319ae4704e5a8526dd27afba4ede

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/1750-1326-5-45

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