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Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG

Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2937031280e43858e2d3edef81ce057

Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG

About this item

Full title

Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG

Publisher

United States: John Wiley & Sons, Inc

Journal title

Annals of Clinical and Translational Neurology, 2024-12, Vol.11 (12), p.3192-3204

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Objective
Recombinant monoclonal therapeutic antibodies like lecanemab, which target amyloid beta in Alzheimer's disease, offer a promising approach for modifying the disease progression. Due to its relatively short half‐life, lecanemab administered as a bi‐monthly infusion (typically 10 mg/kg) has a relatively brief half‐life. Interaction with...

Alternative Titles

Full title

Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a2937031280e43858e2d3edef81ce057

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2937031280e43858e2d3edef81ce057

Other Identifiers

ISSN

2328-9503

E-ISSN

2328-9503

DOI

10.1002/acn3.52227

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