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Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated ep...

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated ep...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2d864d64def4e4f9da5378cdfdff5c4

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

About this item

Full title

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

Publisher

Germany: BioMed Central Ltd

Journal title

Clinical epigenetics, 2019-03, Vol.11 (1), p.52-52, Article 52

Language

English

Formats

Publication information

Publisher

Germany: BioMed Central Ltd

More information

Scope and Contents

Contents

Alzheimer's disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer's disease have been unable to distinguish between DNA methylation and DNA hydroxymethylation. DNA hydroxymethylation has been shown to be enriched in the human brain, although its...

Alternative Titles

Full title

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a2d864d64def4e4f9da5378cdfdff5c4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2d864d64def4e4f9da5378cdfdff5c4

Other Identifiers

ISSN

1868-7075,1868-7083

E-ISSN

1868-7083,1868-7075

DOI

10.1186/s13148-019-0636-y

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