Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated ep...
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease
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Germany: BioMed Central Ltd
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English
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Germany: BioMed Central Ltd
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Alzheimer's disease is a progressive neurodegenerative disorder that is hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in Alzheimer's disease have been unable to distinguish between DNA methylation and DNA hydroxymethylation. DNA hydroxymethylation has been shown to be enriched in the human brain, although its...
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Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_a2d864d64def4e4f9da5378cdfdff5c4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2d864d64def4e4f9da5378cdfdff5c4
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1868-7075,1868-7083
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1868-7083,1868-7075
DOI
10.1186/s13148-019-0636-y