Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis
Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The BCL6 Corepressor (BCOR) is a component of a variant Polycomb repressive complex 1 (PRC1) that is essential for normal development. Recurrent mutations in the
BCOR
gene have been identified in acute myeloid leukaemia and myelodysplastic syndrome among other cancers; however, its function remains poorly understood. Here we examine the role...
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Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_a2e6698ad2f4471982b9c6935cb918b2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2e6698ad2f4471982b9c6935cb918b2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09250-6
