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The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia

The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2f90864bbf54dcfa024ff6935b273d8

The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia

About this item

Full title

The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia

Publisher

United States: Public Library of Science (PLoS)

Journal title

PloS one, 2012, Vol.7 (1), p.e30706-e30706

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science (PLoS)

More information

Scope and Contents

Contents

Ecotropic viral integration site-1 (EVI1) is one of the candidate oncogenes for human acute myeloid leukemia (AML) with chromosomal alterations at 3q26. High EVI1 expression (EVI1(high)) is a risk factor for AML with poor outcome. Using DNA microarray analysis, we previously identified that integrin α6 (ITGA6) was upregulated over 10-fold in EVI1(h...

Alternative Titles

Full title

The increased expression of integrin α6 (ITGA6) enhances drug resistance in EVI1(high) leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a2f90864bbf54dcfa024ff6935b273d8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2f90864bbf54dcfa024ff6935b273d8

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0030706

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