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Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer

Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a304381428d34d3e85cb3c832a330b4b

Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer

About this item

Full title

Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer

Publisher

London: BioMed Central Ltd

Journal title

BMC cancer, 2022-08, Vol.22 (1), p.1-17, Article 940

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

In human colorectal cancer (CRC),
TP53
is one of the most important driver genes. Immunohistochemistry (IHC) has been used most often to assess the variational status of
TP53
. Recently, next-generation sequencing (NGS) of the
TP53
gene has increased. However, to our knowledge, a comparison between
TP53
status evaluated by I...

Alternative Titles

Full title

Clinical significance of p53 protein expression and TP53 variation status in colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a304381428d34d3e85cb3c832a330b4b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a304381428d34d3e85cb3c832a330b4b

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-022-10039-y

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