Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI...
Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male mice
About this item
Full title
Author / Creator
Ye, Qian , Liu, Yi , Zhang, Guiji , Deng, Haijun , Wang, Xiaojun , Tuo, Lin , Chen, Chang , Pan, Xuanming , Wu, Kang , Fan, Jiangao , Pan, Qin , Wang, Kai , Huang, Ailong and Tang, Ni
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Metabolic associated fatty liver disease (MAFLD) encompasses a broad spectrum of hepatic disorders, including steatosis, nonalcoholic steatohepatitis (NASH) and fibrosis. We demonstrated that phosphoenolpyruvate carboxykinase 1 (PCK1) plays a central role in MAFLD progression. Male mice with liver
Pck1
deficiency fed a normal diet displayed h...
Alternative Titles
Full title
Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a30c45d28e9344e29e4f12528c65a86c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a30c45d28e9344e29e4f12528c65a86c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37142-3
