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Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a318d3d553d9469faacc85ade9ab0a76

Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

About this item

Full title

Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2017-07, Vol.9 (7), p.890-905

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hydrocephalus is a common congenital anomaly.
LCAM1
and
MPDZ
(
MUPP1
) are the only known human gene loci associated with non‐syndromic hydrocephalus. To investigate functions of the tight junction‐associated protein Mpdz, we generated mouse models. Global
Mpdz
gene deletion or conditional inactivation in Nestin‐positive cel...

Alternative Titles

Full title

Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a318d3d553d9469faacc85ade9ab0a76

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a318d3d553d9469faacc85ade9ab0a76

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201606430

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