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Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in...

Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a342cb32c73640b4ab603e665e81790d

Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

About this item

Full title

Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

Publisher

England: BioMed Central Ltd

Journal title

Breast cancer research : BCR, 2021-03, Vol.23 (1), p.39-16, Article 39

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Transforming growth factor beta1 (TGFB1) is a multi-functional cytokine that regulates mammary gland development and cancer progression through endocrine, paracrine and autocrine mechanisms. TGFB1 also plays roles in tumour development and progression, and its increased expression is associated with an increased breast cancer risk. Macrophages are...

Alternative Titles

Full title

Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a342cb32c73640b4ab603e665e81790d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a342cb32c73640b4ab603e665e81790d

Other Identifiers

ISSN

1465-542X,1465-5411

E-ISSN

1465-542X

DOI

10.1186/s13058-021-01417-8

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