Selective targeting of IRAK1 attenuates low molecular weight hyaluronic acid-induced stemness and no...
Selective targeting of IRAK1 attenuates low molecular weight hyaluronic acid-induced stemness and non-canonical STAT3 activation in epithelial ovarian cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Advanced epithelial ovarian cancer (EOC) survival rates are dishearteningly low, with ~25% surviving beyond 5 years. Evidence suggests that cancer stem cells contribute to acquired chemoresistance and tumor recurrence. Here, we show that IRAK1 is upregulated in EOC tissues, and enhanced expression correlates with poorer overall survival. Moreover,...
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Selective targeting of IRAK1 attenuates low molecular weight hyaluronic acid-induced stemness and non-canonical STAT3 activation in epithelial ovarian cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_a34cd1f4ae354f69b2bfaed9395015fa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a34cd1f4ae354f69b2bfaed9395015fa
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2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06717-3
